Detalhe da pesquisa
1.
Removal of the vicinal disulfide enhances the platelet-capturing function of von Willebrand factor.
Blood
; 141(12): 1469-1473, 2023 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36603190
2.
MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serum.
PLoS Pathog
; 17(2): e1009283, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33534834
3.
The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction.
Blood
; 133(4): 356-365, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30366922
4.
Arabinose Alters Both Local and Distal H-D Exchange Rates in the Escherichia coli AraC Transcriptional Regulator.
Biochemistry
; 58(26): 2875-2882, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31199144
5.
A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding.
J Biol Chem
; 292(9): 3866-3876, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28057753
6.
Wedging the door open on platelet-type von Willebrand disease.
Br J Haematol
; 203(4): 501-503, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37666663
7.
"Cooperative collapse" of the denatured state revealed through Clausius-Clapeyron analysis of protein denaturation phase diagrams.
Biopolymers
; 109(8): e23106, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29457634
8.
ThANNCs for kinetically optimizing ITC.
Biophys J
; 121(12): 2219-2220, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35660142
9.
Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor.
J Biol Chem
; 291(8): 3848-59, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26677223
10.
Chaperonin-Based Biolayer Interferometry To Assess the Kinetic Stability of Metastable, Aggregation-Prone Proteins.
Biochemistry
; 55(35): 4885-908, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27505032
11.
Structural origins of misfolding propensity in the platelet adhesive von Willebrand factor A1 domain.
Biophys J
; 109(2): 398-406, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26200876
12.
Misfolding of vWF to pathologically disordered conformations impacts the severity of von Willebrand disease.
Biophys J
; 107(5): 1185-1195, 2014 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25185554
13.
Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins.
Proteins
; 82(12): 3373-84, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25244701
14.
A molten globule intermediate of the von Willebrand factor A1 domain firmly tethers platelets under shear flow.
Proteins
; 82(5): 867-78, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24265179
15.
Oxidative refolding of rPA in l-ArgHCl and in ionic liquids: A correlation between hydrophobicity, salt effects, and refolding yield.
Biopolymers
; 101(11): 1129-40, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24931846
16.
Biophysical characterization of human-cell-expressed, full-length κI O18/O8, AL-09, λ6a, and Wil immunoglobulin light chains.
Biochim Biophys Acta Proteins Proteom
; 1872(3): 140993, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38169170
17.
A murine multiple-injury model for the study of thromboinflammation.
J Trauma Acute Care Surg
; 96(2): 203-208, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934621
18.
Free cholesterol determines reassembled high-density lipoprotein phospholipid phase structure and stability.
Biochemistry
; 52(25): 4324-30, 2013 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23721456
19.
N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress.
J Biol Chem
; 287(18): 14579-85, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22431729
20.
A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWD.
Blood Adv
; 6(7): 2236-2246, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619770